Help Center/Cell Encapsulation & Gel Handling

Is QGel MT 3D Matrix injectable in vivo ?

QGel Support
posted this on June 05, 2010 14:08

QGel™ matrices carrying cells can be transplanted to animal tissues to induce and study specific in vivo responses. QGel™ matrices are injectable provided that the injection method is adapted to the gelation time constraint (i.e. 5-10 minutes handling time from powder resuspension to gel solidification). However, physiological liquids (e.g. blood) present at injection site in vivo may dilute the gelling solution of QGel™ MT 3D Matrix, and this may alter gelation time and final mechanical characteristics. For better experimental reproducibility QGel™ recommend to precast discs with encapsulated cells and to implant them subsequently in your in vivo model.