QGel™ MT 3D Matrix is a PEG (poly-ethylen glycol) based material. This polymer is crosslinked into a 3D network with peptides that contain an amino acid sequence that can be cleaved by cell-secreted proteases such as MMPs. Therefore, like in natural matrices, cells are able to degrade the matrix locally via secretion and activation of proteases (MMPs), move further and proliferate. Furthermore, if needed, QGel™ provides gels with covalently-bond RGD peptides to stimulate cell-integrin binding and allow adhesion of the cells to their environment.

To see the components of QGel™ and how it is bioengineered, watch the video Bioengineering QGel™

You can also find more information about the structure and composition of QGel™ MT 3D Matrices, on p.04 and 05 of the QGel™ MT 3D Matrix Product Info brochure (see also the figure below).